Carregant...
A defined structural unit enables de novo design of small-molecule–binding proteins
The de novo design of proteins that bind highly functionalized small molecules represents a great challenge. To enable computational design of binders, we developed a unit of protein structure—a van der Mer (vdM)—that maps the backbone of each amino acid to statistically preferred positions of inter...
Guardat en:
| Publicat a: | Science |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7526616/ https://ncbi.nlm.nih.gov/pubmed/32883865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abb8330 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|