Loading...
A defined structural unit enables de novo design of small-molecule–binding proteins
The de novo design of proteins that bind highly functionalized small molecules represents a great challenge. To enable computational design of binders, we developed a unit of protein structure—a van der Mer (vdM)—that maps the backbone of each amino acid to statistically preferred positions of inter...
Na minha lista:
| Udgivet i: | Science |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7526616/ https://ncbi.nlm.nih.gov/pubmed/32883865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abb8330 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|