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De novo design of catalytic proteins

The de novo design of catalytic proteins provides a stringent test of our understanding of enzyme function, while simultaneously laying the groundwork for the design of novel catalysts. Here we describe the design of an O(2)-dependent phenol oxidase whose structure, sequence, and activity are design...

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Détails bibliographiques
Auteurs principaux: Kaplan, J., DeGrado, W. F.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC511021/
https://ncbi.nlm.nih.gov/pubmed/15292507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404387101
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