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Catalytic efficiency of designed catalytic proteins
The de novo design of catalysts that mimic the affinity and specificity of natural enzymes remains one of the Holy Grails of chemistry. Despite decades of concerted effort we are still unable to design catalysts as efficient as enzymes. Here we critically evaluate approaches to (re)design of novel c...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4182119/ https://ncbi.nlm.nih.gov/pubmed/25048695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2014.06.006 |
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