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Short peptides self-assemble to produce catalytic amyloids

Enzymes fold into unique three-dimensional structures, which underlie their remarkable catalytic properties. The requirement to adopt a stable, folded conformation is likely to contribute to their relatively large size (> 10,000 Dalton). However, much shorter peptides can achieve well-defined con...

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Detalhes bibliográficos
Main Authors: Rufo, Caroline M., Moroz, Yurii S., Moroz, Olesia V., Stöhr, Jan, Smith, Tyler A., Hu, Xiaozhen, DeGrado, William F., Korendovych, Ivan V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996680/
https://ncbi.nlm.nih.gov/pubmed/24651196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1894
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