Genetically Introducing Biochemically Reactive Amino Acids Dehydroalanine and Dehydrobutyrine in Proteins

Expansion of the genetic code with unnatural amino acids (Uaas) has significantly increased the chemical space available to proteins for exploitation. Due to the inherent limitation of translational machinery and the required compatibility with biological settings, function groups introduced via Uaa...

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Udgivet i:J Am Chem Soc
Main Authors: Yang, Bing, Wang, Nanxi, Schnier, Paul D., Zheng, Feng, Zhu, He, Polizzi, Nicholas F., Ittuveetil, Avinash, Saikam, Varma, DeGrado, William F., Wang, Qian, Wang, Peng G., Wang, Lei
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556376/
https://ncbi.nlm.nih.gov/pubmed/31038942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b02611
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