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The Generation of Dehydroalanine Residues in Protonated Polypeptides: Ion/ion Reactions for Introducing Selective Cleavages
We examine a gas-phase approach for converting a sub-set of amino acid residues in polypeptide cations to dehydroalanine (Dha). Subsequent activation of the modified polypeptide ions gives rise to specific cleavage N-terminal to the Dha residue. This process allows for the incorporation of selective...
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| Publicado no: | J Am Soc Mass Spectrom |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5681889/ https://ncbi.nlm.nih.gov/pubmed/28497355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-017-1672-5 |
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