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Characterization of a Computationally Designed Water-soluble Human μ Opioid Receptor Variant Using X-ray Structural Information
BACKGROUND: The recent X-ray crystal structure of the murine μ opioid receptor (MUR) allowed us to reengineer a previously designed water-soluble variant of the transmembrane portion of the human MUR (wsMUR-TM). METHODS: The new variant of water soluble MUR (wsMUR-TM_v2) was engineered based upon th...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4175066/ https://ncbi.nlm.nih.gov/pubmed/24835677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000308 |
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