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The C-terminus of the mu opioid receptor is critical in G-protein interaction as demonstrated by a novel graphene biosensor

Several water-soluble variants of the human mu opioid receptor (wsMORs) have been designed and expressed, which enables the detection of opioids in the nM to pM range using biosensing platforms. The tools previously developed allowed us to investigate MOR and G-protein interactions in a lipid free s...

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Bibliografske podrobnosti
izdano v:IEEE Sens J
Main Authors: Wen, Chengyu, Selling, Bernard, Yeliseev, Alexei, Xi, Jin, Perez-Aguilar, Jose Manuel, Gao, Zhaoli, Saven, Jeffery G., Johnson, A.T. Charlie, Liu, Renyu
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935050/
https://ncbi.nlm.nih.gov/pubmed/33679256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/jsen.2020.3043149
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