Scalable Production of Highly Sensitive Nanosensors Based on Graphene Functionalized with a Designed G Protein-Coupled Receptor

[Image: see text] We have developed a novel, all-electronic biosensor for opioids that consists of an engineered μ-opioid receptor protein, with high binding affinity for opioids, chemically bonded to a graphene field-effect transistor to read out ligand binding. A variant of the receptor protein th...

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Détails bibliographiques
Auteurs principaux: Lerner, Mitchell B., Matsunaga, Felipe, Han, Gang Hee, Hong, Sung Ju, Xi, Jin, Crook, Alexander, Perez-Aguilar, Jose Manuel, Park, Yung Woo, Saven, Jeffery G., Liu, Renyu, Johnson, A. T. Charlie
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2014
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025580/
https://ncbi.nlm.nih.gov/pubmed/24742304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl5006349
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