Agonist-induced formation of unproductive receptor-G(12) complexes

by Okashah, Najeah, Wright, Shane C., Kawakami, Kouki, Mathiasen, Signe, Zhou, Joris, Lu, Sumin, Javitch, Jonathan A., Inoue, Asuka, Bouvier, Michel, Lambert, Nevin A.
Published in Proc Natl Acad Sci U S A (2020)

Electronic tuning of self-healing fluorophores for live-cell and single-molecule imaging

by Zheng, Qinsi, Jockusch, Steffen, Zhou, Zhou, Altman, Roger B., Zhao, Hong, Asher, Wesley, Holsey, Michael, Mathiasen, Signe, Geggier, Peter, Javitch, Jonathan A., Blanchard, Scott C.
Published in Chem Sci (2017)

CALM Regulates Clathrin-Coated Vesicle Size and Maturation by Directly Sensing and Driving Membrane Curvature

by Miller, Sharon E., Mathiasen, Signe, Bright, Nicholas A., Pierre, Fabienne, Kelly, Bernard T., Kladt, Nikolay, Schauss, Astrid, Merrifield, Christien J., Stamou, Dimitrios, Höning, Stefan, Owen, David J.
Published in Dev Cell (2015)

Nanoscale high-content analysis using compositional heterogeneities of single proteoliposomes

by Mathiasen, Signe, Christensen, Sune M, Fung, Juan José, Rasmussen, Søren G F, Fay, Jonathan F, Jorgensen, Sune K, Veshaguri, Salome, Farrens, David L, Kiskowski, Maria, Kobilka, Brian, Stamou, Dimitrios
Published in Nat Methods (2014)

G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3

by Mathiasen, Signe, Palmisano, Tiago, Perry, Nicole A., Stoveken, Hannah M., Vizurraga, Alex, McEwen, Dyke P., Okashah, Najeah, Langenhan, Tobias, Inoue, Asuka, Lambert, Nevin A., Tall, Gregory G., Javitch, Jonathan A.
Published in Nat Chem Biol (2020)

Novel Fluorescent Ligands Enable Single-Molecule Localization Microscopy of the Dopamine Transporter

by Guthrie, Daryl A., Klein Herenbrink, Carmen, Domenic Lycas, Matthew, Ku, Therese, Bonifazi, Alessandro, DeVree, Brian T., Mathiasen, Signe, Javitch, Jonathan A., Grimm, Jonathan B., Lavis, Luke, Gether, Ulrik, Hauck Newman, Amy
Published in ACS Chem Neurosci (2020)

Single-molecule analysis of ligand efficacy in β(2)AR-G protein activation

by Gregorio, G. Glenn, Masureel, Matthieu, Hilger, Daniel, Terry, Daniel S., Juette, Manuel, Zhao, Hong, Zhou, Zhou, Perez-Aguilar, Jose Manuel, Hauge, Maria, Mathiasen, Signe, Javitch, Jonathan A., Weinstein, Harel, Kobilka, Brian K., Blanchard, Scott C.
Published in Nature (2017)

Single Proteoliposome High-Content Analysis Reveals Differences in the Homo-Oligomerization of GPCRs

by Walsh, Samuel M., Mathiasen, Signe, Christensen, Sune M., Fay, Jonathan F., King, Christopher, Provasi, Davide, Borrero, Ernesto, Rasmussen, Søren G.F., Fung, Juan Jose, Filizola, Marta, Hristova, Kalina, Kobilka, Brian, Farrens, David L., Stamou, Dimitrios
Published in Biophys J (2018)

Single-molecule FRET imaging of GPCR dimers in living cells

by Asher, Wesley B., Geggier, Peter, Holsey, Michael D., Gilmore, Grant T., Pati, Avik K., Meszaros, Jozsef, Terry, Daniel S., Mathiasen, Signe, Kaliszewski, Megan J., McCauley, Mitchell D., Govindaraju, Alekhya, Zhou, Zhou, Harikumar, Kaleeckal G., Jaqaman, Khuloud, Miller, Laurence J., Smith, Adam W., Blanchard, Scott C., Javitch, Jonathan A.
Published in Nat Methods (2021)