Agonist-induced formation of unproductive receptor-G(12) complexes

Por Okashah, Najeah, Wright, Shane C., Kawakami, Kouki, Mathiasen, Signe, Zhou, Joris, Lu, Sumin, Javitch, Jonathan A., Inoue, Asuka, Bouvier, Michel, Lambert, Nevin A.
Publicado no Proc Natl Acad Sci U S A (2020)

Electronic tuning of self-healing fluorophores for live-cell and single-molecule imaging

Por Zheng, Qinsi, Jockusch, Steffen, Zhou, Zhou, Altman, Roger B., Zhao, Hong, Asher, Wesley, Holsey, Michael, Mathiasen, Signe, Geggier, Peter, Javitch, Jonathan A., Blanchard, Scott C.
Publicado no Chem Sci (2017)

CALM Regulates Clathrin-Coated Vesicle Size and Maturation by Directly Sensing and Driving Membrane Curvature

Por Miller, Sharon E., Mathiasen, Signe, Bright, Nicholas A., Pierre, Fabienne, Kelly, Bernard T., Kladt, Nikolay, Schauss, Astrid, Merrifield, Christien J., Stamou, Dimitrios, Höning, Stefan, Owen, David J.
Publicado no Dev Cell (2015)

Nanoscale high-content analysis using compositional heterogeneities of single proteoliposomes

Por Mathiasen, Signe, Christensen, Sune M, Fung, Juan José, Rasmussen, Søren G F, Fay, Jonathan F, Jorgensen, Sune K, Veshaguri, Salome, Farrens, David L, Kiskowski, Maria, Kobilka, Brian, Stamou, Dimitrios
Publicado no Nat Methods (2014)

G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3

Por Mathiasen, Signe, Palmisano, Tiago, Perry, Nicole A., Stoveken, Hannah M., Vizurraga, Alex, McEwen, Dyke P., Okashah, Najeah, Langenhan, Tobias, Inoue, Asuka, Lambert, Nevin A., Tall, Gregory G., Javitch, Jonathan A.
Publicado no Nat Chem Biol (2020)

Novel Fluorescent Ligands Enable Single-Molecule Localization Microscopy of the Dopamine Transporter

Por Guthrie, Daryl A., Klein Herenbrink, Carmen, Domenic Lycas, Matthew, Ku, Therese, Bonifazi, Alessandro, DeVree, Brian T., Mathiasen, Signe, Javitch, Jonathan A., Grimm, Jonathan B., Lavis, Luke, Gether, Ulrik, Hauck Newman, Amy
Publicado no ACS Chem Neurosci (2020)

Single-molecule analysis of ligand efficacy in β(2)AR-G protein activation

Por Gregorio, G. Glenn, Masureel, Matthieu, Hilger, Daniel, Terry, Daniel S., Juette, Manuel, Zhao, Hong, Zhou, Zhou, Perez-Aguilar, Jose Manuel, Hauge, Maria, Mathiasen, Signe, Javitch, Jonathan A., Weinstein, Harel, Kobilka, Brian K., Blanchard, Scott C.
Publicado no Nature (2017)

Single Proteoliposome High-Content Analysis Reveals Differences in the Homo-Oligomerization of GPCRs

Por Walsh, Samuel M., Mathiasen, Signe, Christensen, Sune M., Fay, Jonathan F., King, Christopher, Provasi, Davide, Borrero, Ernesto, Rasmussen, Søren G.F., Fung, Juan Jose, Filizola, Marta, Hristova, Kalina, Kobilka, Brian, Farrens, David L., Stamou, Dimitrios
Publicado no Biophys J (2018)

Single-molecule FRET imaging of GPCR dimers in living cells

Por Asher, Wesley B., Geggier, Peter, Holsey, Michael D., Gilmore, Grant T., Pati, Avik K., Meszaros, Jozsef, Terry, Daniel S., Mathiasen, Signe, Kaliszewski, Megan J., McCauley, Mitchell D., Govindaraju, Alekhya, Zhou, Zhou, Harikumar, Kaleeckal G., Jaqaman, Khuloud, Miller, Laurence J., Smith, Adam W., Blanchard, Scott C., Javitch, Jonathan A.
Publicado no Nat Methods (2021)