Reflections on Darwinian Evolution – Is there a Jewish Perspective?

Por Jacob, Chaim O.
Publicado em 2011

Reply to Sawalha: Evidence for IRAK1 is not evidence against MECP2

Por Jacob, Chaim O., Zidovetzki, Raphael, Mohan, Chandra
Publicado em 2009

Function2Gene: A gene selection tool to increase the power of genetic association studies by utilizing public databases and expert knowledge

Por Armstrong, Don L, Jacob, Chaim O, Zidovetzki, Raphael
Publicado em 2008

Systemic Lupus Erythematosus-associated Neutrophil Cytosolic Factor 2 Mutation Affects the Structure of NADPH Oxidase Complex

Por Armstrong, Don L., Eisenstein, Miriam, Zidovetzki, Raphael, Jacob, Chaim O.
Publicado no J Biol Chem (2015)

Development of murine systemic lupus erythematosus in the absence of BAFF

Por Stohl, William, Yu, Ning, Chalmers, Samantha, Putterman, Chaim, Jacob, Chaim O
Publicado no Arthritis Rheumatol (2019)

Constitutive reduction in the checkpoint inhibitor, CTLA-4, does not accelerate SLE in NZM 2328 mice

Por Stohl, William, Yu, Ning, Chalmers, Samantha A, Putterman, Chaim, Jacob, Chaim O
Publicado no Lupus Sci Med (2019)

Admixture in Hispanic-Americans: Its impact on ITGAM association and implications for admixture mapping in SLE

Por Molineros, Julio E., Kim-Howard, Xana, Deshmukh, Harshal, Jacob, Chaim O., Harley, John B., Nath, Swapan K.
Publicado em 2009

Differential Contribution of IL-4 and STAT6 vs STAT4 to the Development of Lupus Nephritis

Por Singh, Ram Raj, Saxena, Vijay, Zang, Song, Li, Lily, Finkelman, Fred D., Witte, David P., Jacob, Chaim O.
Publicado em 2003

B cell- and BAFF-dependence of IFNα-exaggerated disease in SLE-prone NZM 2328 mice

Por Jacob, Noam, Guo, Shunhua, Mathian, Alexis, Koss, Michael N., Gindea, Simona, Putterman, Chaim, Jacob, Chaim O., Stohl, William
Publicado em 2011

Inhibition of B cell activation following in vivo co-engagement of B cell antigen receptor and Fcγ receptor IIb in non-autoimmune-prone and SLE-prone mice

Por Chu, Seung Y., Pong, Erik, Bonzon, Christine, Yu, Ning, Jacob, Chaim O., Chalmers, Samantha A., Putterman, Chaim, Szymkowski, David E., Stohl, William
Publicado no J Transl Autoimmun (2020)

Dispensability of APRIL to development of systemic lupus erythematosus in NZM 2328 mice

Por Jacob, Chaim O., Guo, Shunhua, Jacob, Noam, Pawar, Rahul D., Putterman, Chaim, Quinn, William J., Cancro, Michael P., Migone, Thi-Sau, Stohl, William
Publicado em 2012

Paucity of Clinical Disease despite Serological Autoimmunity and Kidney Pathology in Lupus-Prone New Zealand Mixed 2328 Mice Deficient in BAFF

Por Jacob, Chaim O., Pricop, Luminita, Putterman, Chaim, Koss, Michael N., Liu, Yi, Kollaros, Maria, Bixler, Sarah A., Ambrose, Christine M., Scott, Martin L., Stohl, William
Publicado em 2006

TLR-7-mediated Lupus Nephritis Is Independent of Type I Interferon Signaling

Por Wolf, Sonya J., Theros, Jonathan, Reed, Tammi J., Liu, Jianhua, Grigorova, Irina L., Martínez-Colón, Giovanny, Jacob, Chaim O., Hodgin, Jeffrey B., Kahlenberg, J. Michelle
Publicado no J Immunol (2018)

Essential role and therapeutic targeting of the glomerular endothelial glycocalyx in lupus nephritis

Por Kadoya, Hiroyuki, Yu, Ning, Schiessl, Ina Maria, Riquier-Brison, Anne, Gyarmati, Georgina, Desposito, Dorinne, Kidokoro, Kengo, Butler, Matthew J., Jacob, Chaim O., Peti-Peterdi, János
Publicado no JCI Insight (2020)

Deficiency of type I IFN receptor in lupus-prone NZM 2328 mice decreases dendritic cell numbers and activation and protects from disease

Por Agrawal, Hemant, Jacob, Noam, Carreras, Esther, Bajana, Sandra, Putterman, Chaim, Turner, Sean, Neas, Barbara, Mathian, Alexis, Koss, Michael N., Stohl, William, Kovats, Susan, Jacob, Chaim O.
Publicado em 2009

Development of systemic lupus erythematosus in NZM 2328 mice in the absence of any single BAFF receptor

Por Jacob, Chaim O., Yu, Ning, Guo, Shunhua, Jacob, Noam, Quinn, William J., Sindhava, Vishal, Cancro, Michael P., Goilav, Beatrice, Putterman, Chaim, Migone, Thi-Sau, Stohl, William
Publicado em 2013

Ultraviolet light induces increased T cell activation in lupus-prone mice via type I IFN-dependent inhibition of T regulatory cells

Por Wolf, Sonya J., Estadt, Shannon N., Theros, Jonathan, Moore, Tyson, Ellis, Jason, Liu, Jianhua, Reed, Tamra J., Jacob, Chaim O., Gudjonsson, Johann E., Kahlenberg, J. Michelle
Publicado no J Autoimmun (2019)

Accelerated Pathological and Clinical Nephritis in Systemic Lupus Erythematosus-Prone New Zealand Mixed 2328 Mice Doubly Deficient in TNF Receptor 1 and TNF Receptor 2 via a Th17-A...

Por Jacob, Noam, Yang, Haitao, Pricop, Luminita, Liu, Yi, Gao, Xiaoni, Zheng, Song Guo, Wang, Juhua, Gao, Hua-Xin, Putterman, Chaim, Koss, Michael N., Stohl, William, Jacob, Chaim O.
Publicado em 2009

IgG1 protects against renal disease in a mouse model of cryoglobulinemia

Por Strait, Richard T., Posgai, Monica T., Mahler, Ashley, Barasa, Nathaniel, Jacob, Chaim O., Köhl, Jörg, Ehlers, Marc, Stringer, Keith, Shanmukappa, Shiva Kumar, Witte, David, Hossain, Md Monir, Khodoun, Marat, Herr, Andrew B., Finkelman, Fred D.
Publicado no Nature (2014)

GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region

Por Armstrong, Don L., Zidovetzki, Raphael, Alarcón-Riquelme, Marta E, Tsao, Betty P, Criswell, Lindsey A, Kimberly, Robert P, Harley, John B, Sivils, Kathy L, Vyse, Timothy J, Gaffney, Patrick M., Langefeld, Carl D, Jacob, Chaim O.
Publicado em 2014