What is the meaning of ‘A compound is carcinogenic’?

Por Schrenk, Dieter
Publicado no Toxicol Rep (2018)

A Systematic Screen of FDA-Approved Drugs for Inhibitors of Biological Threat Agents

Por Madrid, Peter B., Chopra, Sidharth, Manger, Ian D., Gilfillan, Lynne, Keepers, Tiffany R., Shurtleff, Amy C., Green, Carol E., Iyer, Lalitha V., Dilks, Holli Hutcheson, Davey, Robert A., Kolokoltsov, Andrey A., Carrion, Ricardo, Patterson, Jean L., Bavari, Sina, Panchal, Rekha G., Warren, Travis K., Wells, Jay B., Moos, Walter H., Burke, RaeLyn L., Tanga, Mary J.
Publicado em 2013

Not like Botryllus: indiscriminate post-metamorphic fusion in a compound ascidian

Por Bishop, J. D. D., Sommerfeldt, A. D.
Publicado em 1999

Biological Studies and Target Engagement of the 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase (IspD)-Targeting Antimalarial Agent (1R,3S)-MMV008138 and Analogs

Por Ghavami, Maryam, Merino, Emilio F., Yao, Zhong-Ke, Elahi, Rubayet, Simpson, Morgan E., Fernández-Murga, Maria L., Butler, Joshua H., Casasanta, Michael A., Krai, Priscilla M., Totrov, Maxim M., Slade, Daniel J., Carlier, Paul R., Cassera, Maria Belen
Publicado no ACS Infect Dis (2017)

Three Dimensional Cellular Microarray Platform for Human Neural Stem Cell Differentiation and Toxicology

Por Meli, Luciana, Barbosa, Hélder S.C., Hickey, Anne Marie, Gasimli, Leyla, Nierode, Gregory, Diogo, Maria Margarida, Linhardt, Robert J., Cabral, Joaquim M.S., Dordick, Jonathan S.
Publicado em 2014

A small-molecule antivirulence agent for treating Clostridium difficile infection

Por Bender, Kristina Oresic, Garland, Megan, Ferreyra, Jessica A., Hryckowian, Andrew J., Child, Matthew A., Puri, Aaron W., Solow-Cordero, David E., Higginbottom, Steven K., Segal, Ehud, Banaei, Niaz, Shen, Aimee, Sonnenburg, Justin L., Bogyo, Matthew
Publicado no Sci Transl Med (2015)

β-d-N(4)-Hydroxycytidine Is a Potent Anti-alphavirus Compound That Induces a High Level of Mutations in the Viral Genome

Por Urakova, Nadya, Kuznetsova, Valeriya, Crossman, David K., Sokratian, Arpine, Guthrie, David B., Kolykhalov, Alexander A., Lockwood, Mark A., Natchus, Michael G., Crowley, Michael R., Painter, George R., Frolova, Elena I., Frolov, Ilya
Publicado no J Virol (2018)

Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters()

Por Hofmaier, Tina, Luf, Anton, Seddik, Amir, Stockner, Thomas, Holy, Marion, Freissmuth, Michael, Ecker, Gerhard F., Schmid, Rainer, Sitte, Harald H., Kudlacek, Oliver
Publicado em 2014

The Stapled AKAP Disruptor Peptide STAD-2 Displays Antimalarial Activity through a PKA-Independent Mechanism

Por Flaherty, Briana R., Wang, Yuxiao, Trope, Edward C., Ho, Tienhuei G., Muralidharan, Vasant, Kennedy, Eileen J., Peterson, David S.
Publicado no PLoS One (2015)

The development and validation of an LC-MS/MS method for the determination of a new anti-malarial compound (TK900D) in human whole blood and its application to pharmacokinetic studies in mice

Por Abay, Efrem T, van der Westhuizen, Jan H, Swart, Kenneth J, Gibhard, Liezl, Tukulula, Matshawandile, Chibale, Kelly, Wiesner, Lubbe
Publicado em 2014

Monkeypox Virus Host Factor Screen Using Haploid Cells Identifies Essential Role of GARP Complex in Extracellular Virus Formation

Por Realegeno, Susan, Puschnik, Andreas S., Kumar, Amrita, Goldsmith, Cynthia, Burgado, Jillybeth, Sambhara, Suryaprakash, Olson, Victoria A., Carroll, Darin, Damon, Inger, Hirata, Tetsuya, Kinoshita, Taroh, Carette, Jan E., Satheshkumar, Panayampalli Subbian
Publicado no J Virol (2017)

Growth inhibition of Escherichia coli and methicillin-resistant Staphylococcus aureus by targeting cellular methionine aminopeptidase

Por Chai, Sergio C., Wang, Wen-Long, Ding, De-Rong, Ye, Qi-Zhuang
Publicado em 2011

Chapter 8 Signalling DNA Damage

Por Lopez-Contreras, Andres Joaquin, Fernandez-Capetillo, Oscar, Joaquin, Andres, Fernandez-Capetillo, Oscar
Publicado em 2012

Role of oxidatively induced DNA lesions in human pathogenesis

Por Sedelnikova, Olga A., Redon, Christophe E., Dickey, Jennifer S., Nakamura, Asako J., Georgakilas, Alexandros G., Bonner, William M.
Publicado em 2010

Rapid detection of fentanyl, fentanyl analogues, and opioids for on-site or laboratory based drug seizure screening using thermal desorption DART-MS and ion mobility spectrometry

Por Sisco, Edward, Verkouteren, Jennifer, Staymates, Jessica, Lawrence, Jeffrey
Publicado no Forensic Chem (2017)

Analysis of Cuticular Lipids of the Pharaoh Ant (Monomorium pharaonis) and Their Selective Adsorption on Insecticidal Zeolite Powders

Por Van Den Noortgate, Heleen, Lagrain, Bert, Wenseleers, Tom, Martens, Johan A.
Publicado no Int J Mol Sci (2018)

Description of outbreaks of healthcare associated infections related to compounding pharmacies, 2000-2012

Por Staes, Catherine, Jacobs, Jason, Mayer, Jeanmarie, Allen, Jill
Publicado em 2013

A Virtual Screen Discovers Novel, Fragment-Sized Inhibitors of Mycobacterium tuberculosis InhA

Por Perryman, Alexander L., Yu, Weixuan, Wang, Xin, Ekins, Sean, Forli, Stefano, Li, Shao-Gang, Freundlich, Joel S., Tonge, Peter J., Olson, Arthur J.
Publicado no J Chem Inf Model (2015)

Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom Helicase

Por Rosenthal, Andrew S., Dexheimer, Thomas S., Gileadi, Opher, Nguyen, Giang H., Chu, Wai Kit, Hickson, Ian D., Jadhav, Ajit, Simeonov, Anton, Maloney, David J.
Publicado em 2013

Predicting the concentration range of unmonitored chemicals in wastewater-dominated streams and in run-off from biosolids-amended soils

Por Chari, Bipin P., Halden, Rolf U.
Publicado em 2012