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Role of oxidatively induced DNA lesions in human pathogenesis

Genome stability is essential for maintaining cellular and organismal homeostasis, but it is subject to many threats. One ubiquitous threat is from a class of compounds known as reactive oxygen species (ROS), which can indiscriminately react with many cellular biomolecules including proteins, lipids...

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Detalhes bibliográficos
Main Authors: Sedelnikova, Olga A., Redon, Christophe E., Dickey, Jennifer S., Nakamura, Asako J., Georgakilas, Alexandros G., Bonner, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074954/
https://ncbi.nlm.nih.gov/pubmed/20060490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2009.12.005
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