Role of oxidatively induced DNA lesions in human pathogenesis

Genome stability is essential for maintaining cellular and organismal homeostasis, but it is subject to many threats. One ubiquitous threat is from a class of compounds known as reactive oxygen species (ROS), which can indiscriminately react with many cellular biomolecules including proteins, lipids...

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Autori principali: Sedelnikova, Olga A., Redon, Christophe E., Dickey, Jennifer S., Nakamura, Asako J., Georgakilas, Alexandros G., Bonner, William M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074954/
https://ncbi.nlm.nih.gov/pubmed/20060490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2009.12.005
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