A small-molecule antivirulence agent for treating Clostridium difficile infection

Clostridium difficile infection (CDI) is a worldwide health threat that is typically triggered by the use of broad-spectrum antibiotics, which disrupt the natural gut microbiota and allow this Gram-positive anaerobic pathogen to thrive. The increased incidence and severity of disease coupled with de...

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Vydáno v:Sci Transl Med
Hlavní autoři: Bender, Kristina Oresic, Garland, Megan, Ferreyra, Jessica A., Hryckowian, Andrew J., Child, Matthew A., Puri, Aaron W., Solow-Cordero, David E., Higginbottom, Steven K., Segal, Ehud, Banaei, Niaz, Shen, Aimee, Sonnenburg, Justin L., Bogyo, Matthew
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025901/
https://ncbi.nlm.nih.gov/pubmed/26400909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aac9103
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