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Growth inhibition of Escherichia coli and methicillin-resistant Staphylococcus aureus by targeting cellular methionine aminopeptidase

Methionine aminopeptidase (MetAP) catalyzes the N-terminal methionine excision from the majority of newly synthesized proteins, which is an essential cotranslational process required for cell survival. As such, MetAP has become an appealing target for the development of antimicrobial therapeutics wi...

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Detalhes bibliográficos
Main Authors: Chai, Sergio C., Wang, Wen-Long, Ding, De-Rong, Ye, Qi-Zhuang
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114176/
https://ncbi.nlm.nih.gov/pubmed/21575996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.04.056
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