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Analysis of the stoichiometric metal activation of methionine aminopeptidase

BACKGROUND: Methionine aminopeptidase (MetAP) is a ubiquitous enzyme required for cell survival and an attractive target for antibacterial and anticancer drug development. The number of a divalent metal required for catalysis is under intense debate. E. coli MetAP was shown to be fully active with o...

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Sonraí Bibleagrafaíochta
Main Authors: Chai, Sergio C, Ye, Qi-Zhuang
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807865/
https://ncbi.nlm.nih.gov/pubmed/20017927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-10-32
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