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Catalysis and inhibition of Mycobacterium tuberculosis methionine aminopeptidase

Methionine aminopeptidase (MetAP) carries out an important cotranslational N-terminal methionine excision of nascent proteins and represents a potential target to develop antibacterial and antitubercular drugs. We cloned one of the two MetAPs in Mycobacterium tuberculosis (MtMetAP1c from the mapB ge...

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Détails bibliographiques
Auteurs principaux: Lu, Jing-Ping, Chai, Sergio C., Ye, Qi-Zhuang
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820511/
https://ncbi.nlm.nih.gov/pubmed/20038112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901624n
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