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Inhibition of Mycobacterium tuberculosis methionine aminopeptidases by bengamide derivatives
Methionine aminopeptidase (MetAP) carries out an essential function of protein N-terminal processing in many bacteria and is a promising target to develop novel antitubercular agents. Natural bengamides potently inhibit proliferation of mammalian cells by targeting MetAP enzymes, and the X-ray struc...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3504309/ https://ncbi.nlm.nih.gov/pubmed/21465667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201100003 |
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