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FE(II) Is the Native Cofactor for Escherichia coli Methionine Aminopeptidase

Divalent metal ions play a critical role in the removal of N-terminal methionine from nascent proteins by methionine aminopeptidase (MetAP). Being an essential enzyme for bacteria, MetAP is an appealing target for the development of novel antibacterial drugs. Although purified enzyme can be activate...

詳細記述

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書誌詳細
主要な著者: Chai, Sergio C., Wang, Wen-Long, Ye, Qi-Zhuang
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556001/
https://ncbi.nlm.nih.gov/pubmed/18669631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804345200
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