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FE(II) Is the Native Cofactor for Escherichia coli Methionine Aminopeptidase
Divalent metal ions play a critical role in the removal of N-terminal methionine from nascent proteins by methionine aminopeptidase (MetAP). Being an essential enzyme for bacteria, MetAP is an appealing target for the development of novel antibacterial drugs. Although purified enzyme can be activate...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2556001/ https://ncbi.nlm.nih.gov/pubmed/18669631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804345200 |
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