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Growth inhibition of Escherichia coli and methicillin-resistant Staphylococcus aureus by targeting cellular methionine aminopeptidase

Methionine aminopeptidase (MetAP) catalyzes the N-terminal methionine excision from the majority of newly synthesized proteins, which is an essential cotranslational process required for cell survival. As such, MetAP has become an appealing target for the development of antimicrobial therapeutics wi...

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Main Authors: Chai, Sergio C., Wang, Wen-Long, Ding, De-Rong, Ye, Qi-Zhuang
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114176/
https://ncbi.nlm.nih.gov/pubmed/21575996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.04.056
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