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The Stapled AKAP Disruptor Peptide STAD-2 Displays Antimalarial Activity through a PKA-Independent Mechanism

Drug resistance poses a significant threat to ongoing malaria control efforts. Coupled with lack of a malaria vaccine, there is an urgent need for the development of new antimalarials with novel mechanisms of action and low susceptibility to parasite drug resistance. Protein Kinase A (PKA) has been...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Flaherty, Briana R., Wang, Yuxiao, Trope, Edward C., Ho, Tienhuei G., Muralidharan, Vasant, Kennedy, Eileen J., Peterson, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444124/
https://ncbi.nlm.nih.gov/pubmed/26010880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129239
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