Isoform-Selective Disruption of AKAP-Localized PKA Using Hydrocarbon Stapled Peptides

[Image: see text] A-kinase anchoring proteins (AKAPs) play an important role in the spatial and temporal regulation of protein kinase A (PKA) by scaffolding critical intracellular signaling complexes. Here we report the design of conformationally constrained peptides that disrupt interactions betwee...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Wang, Yuxiao, Ho, Tienhuei G., Bertinetti, Daniela, Neddermann, Matthias, Franz, Eugen, Mo, Gary C. H., Schendowich, Lewis P., Sukhu, Avinash, Spelts, Raybun C., Zhang, Jin, Herberg, Friedrich W., Kennedy, Eileen J.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985448/
https://ncbi.nlm.nih.gov/pubmed/24422448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400900r
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker