Investigating PKA-RII specificity using analogs of the PKA:AKAP peptide inhibitor STAD-2

Generation of the second messenger molecule cAMP mediates a variety of cellular responses which are essential for critical cellular processes. In response to elevated cAMP levels, cAMP dependent protein kinase (PKA) phosphorylates serine and threonine residues on a wide variety of target substrates....

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Publicat a:Bioorg Med Chem
Autors principals: Bendzunas, N. George, Dörfler, Sabrina, Autenrieth, Karolin, Bertinetti, Daniela, Machal, Erik M. F., Kennedy, Eileen J., Herberg, Friedrich W.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844854/
https://ncbi.nlm.nih.gov/pubmed/29449124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2018.02.001
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