AKAP18:PKA-RIIα structure reveals crucial anchor points for recognition of regulatory subunits of PKA

A-kinase anchoring proteins (AKAPs) interact with the dimerization/docking (D/D) domains of regulatory subunits of the ubiquitous protein kinase A (PKA). AKAPs tether PKA to defined cellular compartments establishing distinct pools to increase the specificity of PKA signalling. Here, we elucidated t...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Götz, Frank, Roske, Yvette, Schulz, Maike Svenja, Autenrieth, Karolin, Bertinetti, Daniela, Faelber, Katja, Zühlke, Kerstin, Kreuchwig, Annika, Kennedy, Eileen J., Krause, Gerd, Daumke, Oliver, Herberg, Friedrich W., Heinemann, Udo, Klussmann, Enno
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964276/
https://ncbi.nlm.nih.gov/pubmed/27102985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160242
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