Regulation of Nuclear PKA revealed by spatiotemporal manipulation of cAMP

Por Sample, Vedangi, DiPilato, Lisa M., Yang, Jason H., Ni, Qiang, Saucerman, Jeffrey J., Zhang, Jin
Publicado em 2012

Cholangiocyte Cilia Detect Changes in Luminal Fluid Flow and Transmit Them into Intracellular Ca(2+) and cAMP Signaling

Por Masyuk, Anatoliy I., Masyuk, Tatyana V., Splinter, Patrick L., Huang, Bing Q., Stroope, Angela J., LaRusso, Nicholas F.
Publicado em 2006

Activation of α7 nicotinic acetylcholine receptors increases intracellular cAMP levels via activation of AC1 in hippocampal neurons

Por Cheng, Qing, Yakel, Jerrel L.
Publicado no Neuropharmacology (2015)

The flavonol glycoside icariin promotes bone formation in growing rats by activating the cAMP signaling pathway in primary cilia of osteoblasts

Por Shi, Wengui, Gao, Yuhai, Wang, Yuanyuan, Zhou, Jian, Wei, Zhenlong, Ma, Xiaoni, Ma, Huiping, Xian, Cory J., Wang, Jufang, Chen, Keming
Publicado no J Biol Chem (2017)

Emerging themes of cAMP regulation of the pulmonary endothelial barrier

Por Sayner, Sarah L.
Publicado no Am J Physiol Lung Cell Mol Physiol (2011)

Luminescence-activated nucleotide cyclase regulates spatial and temporal cAMP synthesis

Por Naim, Nyla, White, Alex D., Reece, Jeff M., Wankhede, Mamta, Zhang, Xuefeng, Vilardaga, Jean-Pierre, Altschuler, Daniel L.
Publicado no J Biol Chem (2019)

17β‐Estradiol reduces mitochondrial cAMP content and cytochrome oxidase activity in a phosphodiesterase 2‐dependent manner

Por Pozdniakova, Sofya, Guitart‐Mampel, Mariona, Garrabou, Gloria, Di Benedetto, Giulietta, Ladilov, Yury, Regitz‐Zagrosek, Vera
Publicado no Br J Pharmacol (2018)

New insights into the dynamic regulation of water and acid-base balance by renal epithelial cells

Por Brown, Dennis, Bouley, Richard, Pǎunescu, Teodor G., Breton, Sylvie, Lu, Hua A. J.
Publicado em 2012

2173: Investigation of sAC signaling reveals new therapeutic targets for cancer cell metabolism

Por Wang, Jenny, Zippin, Jonathan
Publicado no J Clin Transl Sci (2018)

Structure-Activity Relationships of the Sustained Effects of Adenosine A2A Receptor Agonists Driven by Slow Dissociation Kinetics

Por Hothersall, J. Daniel, Guo, Dong, Sarda, Sunil, Sheppard, Robert J., Chen, Hongming, Keur, Wesley, Waring, Michael J., IJzerman, Adriaan P., Hill, Stephen J., Dale, Ian L., Rawlins, Philip B.
Publicado no Mol Pharmacol (2017)

Differential expression of intestinal ion transporters and water channel aquaporins in young piglets challenged with enterotoxigenic Escherichia coli K88

Por Zhu, C., Ye, J. L., Yang, J., Yang, K. M., Chen, Z., Liang, R., Wu, X. J., Wang, L., Jiang, Z. Y.
Publicado no J Anim Sci (2017)

MOD-D, a Galpha subunit of the fungus Podospora anserina, is involved in both regulation of development and vegetative incompatibility.

Por Loubradou, G, Bégueret, J, Turcq, B
Publicado em 1999

Characterization of the putative chloride channel xClC-5 expressed in Xenopus laevis oocytes and comparison with endogenous chloride currents

Por Schmieder, S, Lindenthal, S, Banderali, U, Ehrenfeld, J
Publicado em 1998

Termination and activation of store-operated cyclic AMP production

Por Maiellaro, Isabella, Lefkimmiatis, Konstantinos, Moyer, Mary Pat, Curci, Silvana, Hofer, Aldebaran M
Publicado em 2012

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications

Por Conley, Jason M., Brust, Tarsis F., Xu, Ruqiang, Burris, Kevin D., Watts, Val J.
Publicado em 2014

Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology

Por Podewin, Tom, Ast, Julia, Broichhagen, Johannes, Fine, Nicholas H. F., Nasteska, Daniela, Leippe, Philipp, Gailer, Manuel, Buenaventura, Teresa, Kanda, Nisha, Jones, Ben J., M’Kadmi, Celine, Baneres, Jean-Louis, Marie, Jacky, Tomas, Alejandra, Trauner, Dirk, Hoffmann-Röder, Anja, Hodson, David J.
Publicado no ACS Cent Sci (2018)

Optimization of a 1,3,4-oxadiazole series for inhibition of Ca(2+)/calmodulin-stimulated activity of adenylyl cyclases 1 and 8 for the treatment of chronic pain

Por Kaur, Jatinder, Soto-Velasquez, Monica, Ding, Zhong, Ghanbarpour, Ahmadreza, Lill, Markus A., van Rijn, Richard M., Watts, Val J., Flaherty, Daniel P.
Publicado no Eur J Med Chem (2018)

Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, β-arrestin 2, PDE4D3 complex

Por Halls, Michelle L, Cooper, Dermot M F
Publicado em 2010

Identification of a selective small molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties

Por Brust, Tarsis F., Alongkronrusmee, Doungkamol, Soto-Velasquez, Monica, Baldwin, Tanya A., Ye, Zhishi, Dai, Mingji, Dessauer, Carmen W., van Rijn, Richard M., Watts, Val J.
Publicado no Sci Signal (2017)

Stable G protein-effector complexes in striatal neurons: mechanism of assembly and role in neurotransmitter signaling

Por Xie, Keqiang, Masuho, Ikuo, Shih, Chien-Cheng, Cao, Yan, Sasaki, Keita, Lai, Chun Wan J, Han, Pyung-Lim, Ueda, Hiroshi, Dessauer, Carmen W, Ehrlich, Michelle E, Xu, Baoji, Willardson, Barry M, Martemyanov, Kirill A
Publicado no eLife (2015)