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Regulation of Nuclear PKA revealed by spatiotemporal manipulation of cAMP

Understanding how specific cAMP signals are organized and relayed to their effectors in different compartments of the cell to achieve functional specificity requires molecular tools that allow precise manipulation of cAMP in these compartments. Here we characterize a new method using bicarbonate-act...

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Detalhes bibliográficos
Main Authors: Sample, Vedangi, DiPilato, Lisa M., Yang, Jason H., Ni, Qiang, Saucerman, Jeffrey J., Zhang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307945/
https://ncbi.nlm.nih.gov/pubmed/22366721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.799
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