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Regulation of Nuclear PKA revealed by spatiotemporal manipulation of cAMP

Understanding how specific cAMP signals are organized and relayed to their effectors in different compartments of the cell to achieve functional specificity requires molecular tools that allow precise manipulation of cAMP in these compartments. Here we characterize a new method using bicarbonate-act...

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Bibliographische Detailangaben
Hauptverfasser: Sample, Vedangi, DiPilato, Lisa M., Yang, Jason H., Ni, Qiang, Saucerman, Jeffrey J., Zhang, Jin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307945/
https://ncbi.nlm.nih.gov/pubmed/22366721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.799
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