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Signaling Diversity of PKA Achieved Via a Ca(2+)-cAMP-PKA Oscillatory Circuit
Many protein kinases are key nodal signaling molecules that regulate a wide range of cellular functions. These functions may require complex spatiotemporal regulation of kinase activities. Here, we show that Protein Kinase A (PKA), Ca(2+) and cAMP oscillate in sync in insulin-secreting MIN6 β cells,...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073414/ https://ncbi.nlm.nih.gov/pubmed/21102470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.478 |
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