Spatially compartmentalized phase regulation of a Ca(2+)-cAMP-PKA oscillatory circuit

Signaling networks are spatiotemporally organized to sense diverse inputs, process information, and carry out specific cellular tasks. In β cells, Ca(2+), cyclic adenosine monophosphate (cAMP), and Protein Kinase A (PKA) exist in an oscillatory circuit characterized by a high degree of feedback. Her...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Tenner, Brian, Getz, Michael, Ross, Brian, Ohadi, Donya, Bohrer, Christopher H, Greenwald, Eric, Mehta, Sohum, Xiao, Jie, Rangamani, Padmini, Zhang, Jin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2020
Pynciau:
Biochemistry and Chemical Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671691/
https://ncbi.nlm.nih.gov/pubmed/33201801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55013
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