The Autonomic Nervous System Regulates the Heart Rate through cAMP-PKA Dependent and Independent Coupled-Clock Pacemaker Cell Mechanisms

Sinoatrial nodal cells (SANCs) generate spontaneous action potentials (APs) that control the cardiac rate. The brain modulates SANC automaticity, via the autonomic nervous system, by stimulating membrane receptors that activate (adrenergic) or inactivate (cholinergic) adenylyl cyclase (AC). However,...

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Bibliographic Details
Published in:Front Physiol
Main Authors: Behar, Joachim, Ganesan, Ambhighainath, Zhang, Jin, Yaniv, Yael
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037226/
https://ncbi.nlm.nih.gov/pubmed/27729868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00419
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