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2173: Investigation of sAC signaling reveals new therapeutic targets for cancer cell metabolism
OBJECTIVES/SPECIFIC AIMS: The soluble adenylyl cyclase (sAC) is a noncanonical source of cAMP in mammalian cells. sAC is an ATP/bicarbonate ion sensor, whose activity responds to intracellular signals such as pH changes and metabolism. Unlike the more traditionally studied transmembrane adenylyl cyc...
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| Yayımlandı: | J Clin Transl Sci |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cambridge University Press
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6799008/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2017.25 |
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