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EXPRESSION OF SOLUBLE ADENYLYL CYCLASE (sAC) IN LENTIGO MALIGNA: USE OF IMMUNOHISTOCHEMISTRY WITH anti-sAC ANTIBODY (R21), IN DIAGNOSIS OF LENTIGO MALIGNA AND ASSESMENT OF MARGINS
BACKGROUND: Soluble adenylyl cyclase (sAC) is an enzyme that generates cyclic adenosine monophosphate (cAMP), a signaling molecule involved in regulating melanocyte differentiation, proliferation and melanogenesis. R21, a mouse monoclonal antibody against sAC, shows a pattern of pan nuclear staining...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3732207/ https://ncbi.nlm.nih.gov/pubmed/23194049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5858/arpa.2011-0617-OA |
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