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pH sensing via bicarbonate-regulated “soluble” adenylyl cyclase (sAC)
Soluble adenylyl cyclase (sAC) is a source of the second messenger cyclic adenosine 3′, 5′ monophosphate (cAMP). sAC is directly regulated by bicarbonate (HCO(−)(3)) ions. In living cells, HCO(−)(3) ions are in nearly instantaneous equilibrium with carbon dioxide (CO(2)) and pH due to the ubiquitous...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3838963/ https://ncbi.nlm.nih.gov/pubmed/24324443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00343 |
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