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Role of the bicarbonate-responsive soluble adenylyl cyclase in pH sensing and metabolic regulation
The evolutionarily conserved soluble adenylyl cyclase (sAC, adcy10) was recently identified as a unique source of cAMP in the cytoplasm and the nucleus. Its activity is regulated by bicarbonate and fine-tuned by calcium. As such, and in conjunction with carbonic anhydrase (CA), sAC constitutes an HC...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3918592/ https://ncbi.nlm.nih.gov/pubmed/24575049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00042 |
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