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Bicarbonate, carbon dioxide and pH sensing via mammalian bicarbonate-regulated soluble adenylyl cyclase

Soluble adenylyl cyclase (sAC; ADCY10) is a bicarbonate (HCO(3)(−))-regulated enzyme responsible for the generation of cyclic adenosine monophosphate (cAMP). sAC is distributed throughout the cell and within organelles and, as such, plays a role in numerous cellular signalling pathways. Carbonic anh...

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Vydáno v:Interface Focus
Hlavní autoři: Rossetti, Tom, Jackvony, Stephanie, Buck, Jochen, Levin, Lonny R.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898154/
https://ncbi.nlm.nih.gov/pubmed/33633833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsfs.2020.0034
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