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Bicarbonate-sensing soluble adenylyl cyclase is an essential sensor for acid/base homeostasis
pH homeostasis is essential for life, yet it remains unclear how animals sense their systemic acid/base (A/B) status. Soluble adenylyl cyclase (sAC) is an evolutionary conserved signaling enzyme that produces the second messenger cAMP in response to bicarbonate ions (HCO(3)(−)). We cloned the sAC or...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806762/ https://ncbi.nlm.nih.gov/pubmed/20018667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911790107 |
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