The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein

cAMP signaling pathways can both stimulate and inhibit the development of cancer; however, the sources of cAMP important for tumorigenesis remain poorly understood. Soluble adenylyl cyclase (sAC) is a non-canonical, evolutionarily conserved, nutrient- and pH-sensing source of cAMP. sAC has been impl...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ramos-Espiritu, Lavoisier, Diaz, Ana, Nardin, Charlee, Saviola, Anthony J., Shaw, Fiona, Plitt, Tamar, Yang, Xia, Wolchok, Jedd, Pirog, Edyta C., Desman, Garrett, Sboner, Andrea, Zhang, Tuo, Xiang, Jenny, Merghoub, Taha, Levin, Lonny R., Buck, Jochen, Zippin, Jonathan H.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216745/
https://ncbi.nlm.nih.gov/pubmed/27323809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10056
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