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Pharmacological Distinction between Soluble and Transmembrane Adenylyl Cyclases

The second messenger cAMP is involved in a number of cellular signaling pathways. In mammals, cAMP is produced by either the hormonally responsive, G protein–regulated transmembrane adenylyl cyclases (tmACs) or by the bicarbonate- and calcium-regulated soluble adenylyl cyclase (sAC). To develop tool...

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Detalles Bibliográficos
Main Authors: Bitterman, Jacob L., Ramos-Espiritu, Lavoisier, Diaz, Ana, Levin, Lonny R., Buck, Jochen
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836311/
https://ncbi.nlm.nih.gov/pubmed/24091307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.208496
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