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2173: Investigation of sAC signaling reveals new therapeutic targets for cancer cell metabolism

OBJECTIVES/SPECIFIC AIMS: The soluble adenylyl cyclase (sAC) is a noncanonical source of cAMP in mammalian cells. sAC is an ATP/bicarbonate ion sensor, whose activity responds to intracellular signals such as pH changes and metabolism. Unlike the more traditionally studied transmembrane adenylyl cyc...

詳細記述

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書誌詳細
出版年:J Clin Transl Sci
主要な著者: Wang, Jenny, Zippin, Jonathan
フォーマット: Artigo
言語:Inglês
出版事項: Cambridge University Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799008/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2017.25
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