Study of the docking of competitive inhibitors at a model of tyrosinase active site: insights from...

Por de la Lande, A., Maddaluno, J., Parisel, O., Darden, T. A., Piquemal, J-P
Publicado em 2010

Evaluation of NTF1836 as an inhibitor of the mycothiol biosynthetic enzyme MshC in growing and non-replicating Mycobacterium tuberculosis

Por Newton, Gerald L., Buchmeier, Nancy, La Clair, James J., Fahey, Robert C.
Publicado em 2011

Antimicrobial activity, acute toxicity and cytoprotective effect of Crassocephalum vitellinum (Benth.) S. Moore extract in a rat ethanol-HCl gastric ulcer model

Por Moshi, Mainen J, Nondo, Ramadhani SO, Haule, Emmanuel E, Mahunnah, Rogasian LA, Kidukuli, Abdul W
Publicado em 2014

Activity of the novel BCR kinase inhibitor IQS019 in preclinical models of B-cell non-Hodgkin lymphoma

Por Balsas, P., Esteve-Arenys, A., Roldán, J., Jiménez, L., Rodríguez, V., Valero, J. G., Chamorro-Jorganes, A., de la Bellacasa, R. Puig, Teixidó, J., Matas-Céspedes, A., Moros, A., Martínez, A., Campo, E., Sáez-Borderías, A., Borrell, J. I., Pérez-Galán, P., Colomer, D., Roué, G.
Publicado no J Hematol Oncol (2017)

Epidemiological Trends Strongly Suggest Exposures as Etiologic Agents in the Pathogenesis of Sporadic Alzheimer's Disease, Diabetes Mellitus, and Non-Alcoholic Steatohepatitis

Por de la Monte, Suzanne M., Neusner, Alexander, Chu, Jennifer, Lawton, Margot
Publicado no J Alzheimers Dis (2009)

Conformational changes and translocation of tissue-transglutaminase to the plasma membranes: role in cancer cell migration

Por Kumar, Ambrish, Hu, Jianjun, LaVoie, Holly A, Walsh, Kenneth B, DiPette, Donald J, Singh, Ugra S
Publicado em 2014

Characterization of the Effects of Aryl-Azido Compounds and UVA Irradiation on the Viral Proteins and Infectivity of Human Immunodeficiency Virus Type 1

Por Belanger, Julie M., Raviv, Yossef, Viard, Mathias, de la Cruz, M. Jason, Nagashima, Kunio, Blumenthal, Robert
Publicado em 2010

Inhibition of the hypoxia-inducible factor pathway by a G-quadruplex binding small molecule

Por Welsh, Sarah J., Dale, Aaron G., Lombardo, Caterina M., Valentine, Helen, de la Fuente, Maria, Schatzlein, Andreas, Neidle, Stephen
Publicado em 2013

Valproic acid protects against haemorrhagic shock‐induced signalling changes via PPARγ activation in an in vitro model

Por Zuckermann, Alexandra M E, La Ragione, Roberto M, Baines, Deborah L, Williams, Robin S B
Publicado no Br J Pharmacol (2015)

Two Novel α7 Nicotinic Acetylcholine Receptor Ligands: In Vitro Properties and Their Efficacy in Collagen-Induced Arthritis in Mice

Por van Maanen, Marjolein A., Papke, Roger L., Koopman, Frieda A., Koepke, Jessica, Bevaart, Lisette, Clark, Roger, Lamppu, Diana, Elbaum, Daniel, LaRosa, Gregory J., Tak, Paul P., Vervoordeldonk, Margriet J.
Publicado no PLoS One (2015)

Transmission of Vibrio cholerae Is Antagonized by Lytic Phage and Entry into the Aquatic Environment

Por Nelson, Eric J., Chowdhury, Ashrafuzzaman, Flynn, James, Schild, Stefan, Bourassa, Lori, Shao, Yue, LaRocque, Regina C., Calderwood, Stephen B., Qadri, Firdausi, Camilli, Andrew
Publicado em 2008

Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing

Por Chlebowski, Anna C., La Du, Jane K., Truong, Lisa, Massey Simonich, Staci L., Tanguay, Robert L.
Publicado no Toxicol Rep (2017)

Screening for angiogenic inhibitors in zebrafish to evaluate a predictive model for developmental vascular toxicity

Por Tal, Tamara, Kilty, Claire, Smith, Andrew, LaLone, Carlie, Kennedy, Brendán, Tennant, Alan, McCollum, Catherine W., Bondesson, Maria, Knudsen, Thomas, Padilla, Stephanie, Kleinstreuer, Nicole
Publicado no Reprod Toxicol (2016)

In Vivo Optical Imaging of Brain Tumors and Arthritis Using Fluorescent SapC-DOPS Nanovesicles

Por Chu, Zhengtao, LaSance, Kathleen, Blanco, Victor, Kwon, Chang-Hyuk, Kaur, Balveen, Frederick, Malinda, Thornton, Sherry, Lemen, Lisa, Qi, Xiaoyang
Publicado em 2014

Robust Central Reduction of Amyloid-β in Humans with an Orally Available, Non-Peptidic β-Secretase Inhibitor

Por May, Patrick C., Dean, Robert A., Lowe, Stephen L., Martenyi, Ferenc, Sheehan, Scott M., Boggs, Leonard N., Monk, Scott A., Mathes, Brian M., Mergott, Dustin J., Watson, Brian M., Stout, Stephanie L., Timm, David E., Smith LaBell, Elizabeth, Gonzales, Celedon R., Nakano, Masako, Jhee, Stanford S., Yen, Mark, Ereshefsky, Larry, Lindstrom, Terry D., Calligaro, David O., Cocke, Patrick J., Greg Hall, D., Friedrich, Stuart, Citron, Martin, Audia, James E.
Publicado no J Neurosci (2011)

The Novel Capsazepine Analog, CIDD-99, Significantly Inhibits Oral Squamous Cell Carcinoma In Vivo Through a TRPV1-Independent Induction of ER Stress, Mitochondrial Dysfunction, and Apoptosis

Por De La Chapa, Jorge J., Singha, Prajjal K., Self, Kristen K., Sallaway, McKay L., McHardy, Stanton F., Hart, Matthew, McGuff, H. Stan, Valdez, Matthew C., Ruiz, Francisco, Polusani, Srikanth R., Gonzales, Cara B.
Publicado no J Oral Pathol Med (2019)

Phase II randomized study of PM01183 versus topotecan in patients with platinum-resistant/refractory advanced ovarian cancer

Por Poveda, A., del Campo, J. M., Ray-Coquard, I., Alexandre, J., Provansal, M., Guerra Alía, E. M., Casado, A., Gonzalez-Martin, A., Fernández, C., Rodriguez, I., Soto, A., Kahatt, C., Fernández Teruel, C., Galmarini, C. M., Pérez de la Haza, A., Bohan, P., Berton-Rigaud, D.
Publicado no Ann Oncol (2017)

Flexible Thick-Film Electrochemical Sensors: Impact of Mechanical Bending and Stress on the Electrochemical Behavior

Por Cai, Jiaying, Cizek, Karel, Long, Brenton, McAferty, Kenyon, Campbell, Casey G., Allee, David R., Vogt, Bryan D., La Belle, Jeff, Wang, Joseph
Publicado em 2009

Antistaphylococcal activity of DNA-interactive pyrrolobenzodiazepine (PBD) dimers and PBD-biaryl conjugates

Por Rahman, Khondaker M., Rosado, Helena, Moreira, Joao B., Feuerbaum, Eva-Anne, Fox, Keith R., Stecher, Eva, Howard, Philip W., Gregson, Stephen J., James, Colin H., de la Fuente, Maria, Waldron, Denise E., Thurston, David E., Taylor, Peter W.
Publicado em 2012

New pyrazolo-[3,4-d]-pyrimidine derivative Src kinase inhibitors lead to cell cycle arrest and tumor growth reduction of human medulloblastoma cells

Por Rossi, Alessandra, Schenone, Silvia, Angelucci, Adriano, Cozzi, Martina, Caracciolo, Valentina, Pentimalli, Francesca, Puca, Andrew, Pucci, Biagio, La Montagna, Raffaele, Bologna, Mauro, Botta, Maurizio, Giordano, Antonio
Publicado em 2010