New pyrazolo-[3,4-d]-pyrimidine derivative Src kinase inhibitors lead to cell cycle arrest and tumor growth reduction of human medulloblastoma cells

Medulloblastoma is the most common malignant brain tumor in children, and despite improvements in the overall survival rate, it still lacks an effective treatment. Src plays an important role in cancer, and recently high Src activity was documented in medulloblastoma. In this report, we examined the...

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Bibliografiset tiedot
Päätekijät: Rossi, Alessandra, Schenone, Silvia, Angelucci, Adriano, Cozzi, Martina, Caracciolo, Valentina, Pentimalli, Francesca, Puca, Andrew, Pucci, Biagio, La Montagna, Raffaele, Bologna, Mauro, Botta, Maurizio, Giordano, Antonio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Federation of American Societies for Experimental Biology 2010
Aiheet:
Research Communications
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909284/
https://ncbi.nlm.nih.gov/pubmed/20354138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-148593
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