Pharmacogenetics in model systems: Defining a common mechanism of action for mood stabilisers

由 Williams, Robin S.B.
出版 2005

Bio-electrospraying and aerodynamically assisted bio-jetting the model eukaryotic Dictyostelium discoideum: assessing stress and developmental competency post treatment

由 Pakes, Nicholl K., Jayasinghe, Suwan N., Williams, Robin S. B.
出版 2011

Seizure-induced reduction in PIP(3) levels contributes to seizure-activity and is rescued by valproic acid()

由 Chang, Pishan, Walker, Matthew C., Williams, Robin S.B.
出版 2014

Non-Catalytic Roles of Presenilin Throughout Evolution

由 Otto, Grant P., Sharma, Devdutt, Williams, Robin S.B.
發表在 J Alzheimers Dis (2016)

All You Need Is Fats—for Seizure Control: Using Amoeba to Advance Epilepsy Research

由 Warren, Eleanor C., Walker, Matthew C., Williams, Robin S. B.
發表在 Front Cell Neurosci (2018)

Molecular pharmacology in a simple model system: Implicating MAP kinase and phosphoinositide signalling in bipolar disorder

由 Ludtmann, Marthe H.R., Boeckeler, Katrina, Williams, Robin S.B.
出版 2011

Zizimin and Dock guanine nucleotide exchange factors in cell function and disease

由 Pakes, Nicholl K., Veltman, Douwe M., Williams, Robin S.B.
出版 2013

Diacylglycerol kinase (DGKA) regulates the effect of the epilepsy and bipolar disorder treatment valproic acid in Dictyostelium discoideum

由 Kelly, Elizabeth, Sharma, Devdutt, Wilkinson, Christopher J., Williams, Robin S. B.
發表在 Dis Model Mech (2018)

Valproic acid protects against haemorrhagic shock‐induced signalling changes via PPARγ activation in an in vitro model

由 Zuckermann, Alexandra M E, La Ragione, Roberto M, Baines, Deborah L, Williams, Robin S B
發表在 Br J Pharmacol (2015)

Gamma secretase orthologs are required for lysosomal activity and autophagic degradation in Dictyostelium discoideum, independent of PSEN (presenilin) proteolytic function

由 Sharma, Devdutt, Otto, Grant, Warren, Eleanor C., Beesley, Philip, King, Jason S., Williams, Robin S. B.
發表在 Autophagy (2019)

Investigating the Effect of Emetic Compounds on Chemotaxis in Dictyostelium Identifies a Non-Sentient Model for Bitter and Hot Tastant Research

由 Robery, Steven, Mukanowa, Janina, Percie du Sert, Nathalie, Andrews, Paul L. R., Williams, Robin S. B.
出版 2011

Seizure control by ketogenic diet-associated medium chain fatty acids

由 Chang, Pishan, Terbach, Nicole, Plant, Nick, Chen, Philip E., Walker, Matthew C., Williams, Robin S.B.
出版 2013

Identifying an uptake mechanism for the antiepileptic and bipolar disorder treatment valproic acid using the simple biomedical model Dictyostelium

由 Terbach, Nicole, Shah, Rishita, Kelemen, Rachel, Klein, Peter S., Gordienko, Dmitri, Brown, Nigel A., Wilkinson, Christopher J., Williams, Robin S. B.
出版 2011

A novel human receptor involved in bitter tastant detection identified using Dictyostelium discoideum

由 Robery, Steven, Tyson, Richard, Dinh, Christopher, Kuspa, Adam, Noegel, Angelika A., Bretschneider, Till, Andrews, Paul L. R., Williams, Robin S. B.
發表在 J Cell Sci (2013)

The mood stabiliser lithium suppresses PIP(3) signalling in Dictyostelium and human cells

由 King, Jason S., Teo, Regina, Ryves, Jonathan, Reddy, Jonathan V., Peters, Owen, Orabi, Ben, Hoeller, Oliver, Williams, Robin S. B., Harwood, Adrian J.
出版 2009

Decanoic acid inhibits mTORC1 activity independent of glucose and insulin signaling

由 Warren, Eleanor C., Dooves, Stephanie, Lugarà, Eleonora, Damstra-Oddy, Joseph, Schaf, Judith, Heine, Vivi M., Walker, Mathew C., Williams, Robin S. B.
發表在 Proc Natl Acad Sci U S A (2020)

RpkA, a Highly Conserved GPCR with a Lipid Kinase Domain, Has a Role in Phagocytosis and Anti-Bacterial Defense

由 Riyahi, Tanja Y., Frese, Frederike, Steinert, Michael, Omosigho, Napoleon N., Glöckner, Gernot, Eichinger, Ludwig, Orabi, Benoit, Williams, Robin S. B., Noegel, Angelika A.
出版 2011

Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds

由 Elphick, Lucy M., Pawolleck, Nadine, Guschina, Irina A., Chaieb, Leila, Eikel, Daniel, Nau, Heinz, Harwood, John L., Plant, Nick J., Williams, Robin S. B.
出版 2012

Curcumin and derivatives function through protein phosphatase 2A and presenilin orthologues in Dictyostelium discoideum

由 Cocorocchio, Marco, Baldwin, Amy J., Stewart, Balint, Kim, Lou, Harwood, Adrian J., Thompson, Christopher R. L., Andrews, Paul L. R., Williams, Robin S. B.
發表在 Dis Model Mech (2018)

Attenuation of Phospholipid Signaling Provides a Novel Mechanism for the Action of Valproic Acid

由 Xu, Xuehua, Müller-Taubenberger, Annette, Adley, Kathryn E., Pawolleck, Nadine, Lee, Vivian W. Y., Wiedemann, Claudia, Sihra, Talvinder S., Maniak, Markus, Jin, Tian, Williams, Robin S. B.
出版 2007