Diacylglycerol kinase (DGKA) regulates the effect of the epilepsy and bipolar disorder treatment valproic acid in Dictyostelium discoideum

Valproic acid (VPA) provides a common treatment for both epilepsy and bipolar disorder; however, common cellular mechanisms relating to both disorders have yet to be proposed. Here, we explore the possibility of a diacylglycerol kinase (DGK) playing a role in regulating the effect of VPA relating to...

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Bibliographic Details
Published in:Dis Model Mech
Main Authors: Kelly, Elizabeth, Sharma, Devdutt, Wilkinson, Christopher J., Williams, Robin S. B.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176992/
https://ncbi.nlm.nih.gov/pubmed/30135067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.035600
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