Investigating the Effect of Emetic Compounds on Chemotaxis in Dictyostelium Identifies a Non-Sentient Model for Bitter and Hot Tastant Research

Novel chemical entities (NCEs) may be investigated for emetic liability in a range of unpleasant experiments involving retching, vomiting or conditioned taste aversion/food avoidance in sentient animals. We have used a range of compounds with known emetic /aversive properties to examine the possibil...

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Bibliografiske detaljer
Main Authors: Robery, Steven, Mukanowa, Janina, Percie du Sert, Nathalie, Andrews, Paul L. R., Williams, Robin S. B.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169598/
https://ncbi.nlm.nih.gov/pubmed/21931717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024439
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