Relationship between Dose, Drug Levels, and D2 Receptor Occupancy for the Atypical Antipsychotics Risperidone and Paliperidone

Por Muly, E. C., Votaw, J. R., Ritchie, J., Howell, L. L.
Publicado em 2012

Anticancer activity of streptochlorin, a novel antineoplastic agent, in cholangiocarcinoma

Por Kwak, Tae Won, Shin, Hee Jae, Jeong, Young-Il, Han, Myoung-Eun, Oh, Sae-Ock, Kim, Hyun-Jung, Kim, Do Hyung, Kang, Dae Hwan
Publicado no Drug Des Devel Ther (2015)

Using Chimeric Mice with Humanized Livers to Predict Human Drug Metabolism and a Drug-Drug Interaction

Por Nishimura, Toshiko, Hu, Yajing, Wu, Manhong, Pham, Edward, Suemizu, Hiroshi, Elazar, Menashe, Liu, Michael, Idilman, Ramazan, Yurdaydin, Cihan, Angus, Peter, Stedman, Catherine, Murphy, Brian, Glenn, Jeffrey, Nakamura, Masato, Nomura, Tatsuji, Chen, Yuan, Zheng, Ming, Fitch, William L., Peltz, Gary
Publicado em 2013

Clozapine-Related EEG Changes and Seizures: Dose and Plasma-Level Relationships

Por Varma, Seema, Bishara, Delia, Besag, Frank M. C., Taylor, David
Publicado em 2011

Drug-drug interaction between isavuconazole and tacrolimus: a case report indicating the need for tacrolimus drug-level monitoring

Por Kim, Tiffany, Jancel, Timothy, Kumar, Parag, Freeman, Alexandra F.
Publicado no J Clin Pharm Ther (2015)

Use of glomerular filtration rate estimating equations for drug dosing in HIV-positive patients

Por Okparavero, Aghogho A, Tighiouart, Hocine, Krishnasami, Zipporah, Wyatt, Christina M, Graham, Hiba, Hellinger, James, Inker, Lesley A
Publicado em 2013

Variation in dose and plasma level of lamotrigine in patients discharged from a mental health trust

Por Douglas-Hall, Petrina, Dzahini, Olubanke, Gaughran, Fiona, Bile, Ahmed, Taylor, David
Publicado no Ther Adv Psychopharmacol (2016)

Colocalized Delivery of Rapamycin and Paclitaxel to Tumors Enhances Synergistic Targeting of the PI3K/Akt/mTOR Pathway

Por Blanco, Elvin, Sangai, Takafumi, Wu, Suhong, Hsiao, Angela, Ruiz-Esparza, Guillermo U, Gonzalez-Delgado, Carlos A, Cara, Francisca E, Granados-Principal, Sergio, Evans, Kurt W, Akcakanat, Argun, Wang, Ying, Do, Kim-Anh, Meric-Bernstam, Funda, Ferrari, Mauro
Publicado em 2014

Super-compact treatment with a high dose of moxifloxacin in patients with drug-resistant tuberculosis and its resistance mechanisms

Por WANG, QINGJIANG, ZHANG, CHUNXIAO, GUO, JINHUI, HUANG, JIAN, XI, XIUE, ZHANG, LIGONG, CUI, XIUQIN
Publicado no Exp Ther Med (2015)

Increased levels of urinary phenylacetylglycine associated with mitochondrial toxicity in a model of drug-induced phospholipidosis

Por Doessegger, Lucette, Schmitt, Georg, Lenz, Barbara, Fischer, Holger, Schlotterbeck, Götz, Atzpodien, Elke-Astrid, Senn, Hans, Suter, Laura, Csato, Miklos, Evers, Stefan, Singer, Thomas
Publicado em 2013

Mesenchymal stem cell-derived exosomes promote hepatic regeneration in drug-induced liver injury models

Por Tan, Cheau Yih, Lai, Ruenn Chai, Wong, Winnie, Dan, Yock Young, Lim, Sai-Kiang, Ho, Han Kiat
Publicado no Stem Cell Res Ther (2014)

Repeated Administration of a Mutant Cocaine Esterase: Effects on Plasma Cocaine Levels, Cocaine...

Por Collins, Gregory T., Brim, Remy L., Noon, Kathleen R., Narasimhan, Diwahar, Lukacs, Nicholas W., Sunahara, Roger K., Woods, James H., Ko, Mei-Chuan
Publicado em 2012

Molecular Pharmacodynamics-Guided Scheduling of Biologically Effective Doses: A Drug Development Paradigm Applied to MET Tyrosine Kinase Inhibitors

Por Srivastava, Apurva K., Hollingshead, Melinda G., Govindharajulu, Jeevan P., Covey, Joseph M., Liston, Dane, Simpson, Melanie A., Peggins, James O., Bottaro, Donald P., Wright, John J., Kinders, Robert J., Doroshow, James H., Parchment, Ralph E.
Publicado no Mol Cancer Ther (2018)

Effect of varying doses of tamoxifen on ovarian histopathology, serum VEGF, and endothelin 1 levels in ovarian hyperstimulation syndrome: an experimental study

Por Pala, Şehmus, Atilgan, Remzi, Ozkan¹, Zehra Sema, Kavak, Salih Burçin, Ilhan, Nevin, Akpolat, Nusret, Sapmaz, Ekrem
Publicado no Drug Des Devel Ther (2015)

Optimizing clopidogrel dose response: a new clinical algorithm comprising CYP2C19 pharmacogenetics and drug interactions

Por Saab, Yolande B, Zeenny, Rony, Ramadan, Wijdan H
Publicado no Ther Clin Risk Manag (2015)

On the attenuation and amplification of molecular noise in genetic regulatory networks

Por Chen, Bor-Sen, Wang, Yu-Chao
Publicado em 2006

Phase I Combination of Sorafenib and Erlotinib Therapy in Solid Tumors: Safety, Pharmacokinetic and Pharmacodynamic Evaluation from an Expansion Cohort

Por Quintela-Fandino, Miguel, Le Tourneau, Christophe, Duran, Ignacio, Chen, Eric X., Wang, Lisa, Tsao, Ming, Bandarchi-Chamkhaleh, Bizhan, Pham, Nhu-Ann, Do, Trevor, MacLean, Martha, Nayyar, Rakesh, Tusche, Michael W., Metser, Ur, Wright, John J., Mak, Tak W., Siu, Lillian L.
Publicado em 2010

The role of noise and positive feedback in the onset of autosomal dominant diseases

Por Bosl, William J, Li, Rong
Publicado em 2010

Time and dose relationships between schisandrin B- and schisandrae fructus oil-induced...

Por Zhang, Yi, Pan, Si-Yuan, Zhou, Shu-Feng, Wang, Xiao-Yan, Sun, Nan, Zhu, Pei-Li, Chu, Zhu-Sheng, Yu, Zhi-Ling, Ko, Kam-Ming
Publicado em 2014

A comparison of adeB gene expression levels under conditions of induced resistance by different drugs in vitro in Acinetobacter baumannii

Por Zhu, Wan, Wang, Hui, Zhang, Jing-Ping
Publicado no Exp Ther Med (2017)