Mechanistic insights into GPCR-G protein interactions

Tekijä Mahoney, Jacob P., Sunahara, Roger K.
Julkaisussa Curr Opin Struct Biol (2016)

Reconstitution of G protein-Coupled Receptors into a Model Bilayer System: Reconstituted High Density Lipoprotein Particles (rHDL)

Tekijä Vélez-Ruiz, Gisselle A., Sunahara, Roger K.
Julkaistu 2011

Bacterial cocaine esterase: a protein-based therapy for cocaine overdose and addiction

Tekijä Narasimhan, Diwahar, Woods, James H, Sunahara, Roger K
Julkaistu 2012

Functional dissection of the N-terminal extracellular domains of Frizzled 6 reveals their roles for receptor localization and Dishevelled recruitment

Tekijä Valnohova, Jana, Kowalski-Jahn, Maria, Sunahara, Roger K., Schulte, Gunnar
Julkaisussa J Biol Chem (2018)

ER/K linked GPCR-G protein fusions systematically modulate second messenger response in cells

Tekijä Malik, Rabia U., Dysthe, Matthew, Ritt, Michael, Sunahara, Roger K., Sivaramakrishnan, Sivaraj
Julkaisussa Sci Rep (2017)

Prevention and reversal by cocaine esterase of cocaine-induced cardiovascular effects in rats

Tekijä Wood, Susan K., Narasimhan, Diwahar, Cooper, Ziva, Sunahara, Roger K., Woods, James H.
Julkaistu 2009

Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor

Tekijä Livingston, Kathryn E, Mahoney, Jacob P, Manglik, Aashish, Sunahara, Roger K, Traynor, John R
Julkaisussa eLife (2018)

Identification of GPCR-Interacting Cytosolic Proteins Using HDL Particles and Mass Spectrometry-Based Proteomic Approach

Tekijä Chung, Ka Young, Day, Peter W., Vélez-Ruiz, Gisselle, Sunahara, Roger K., Kobilka, Brian K.
Julkaistu 2013

Evaluation of the Hydrolytic Activity of a Long-Acting Mutant Bacterial Cocaine in the Presence of Commonly Co-Administered Drugs

Tekijä Brim, Remy L., Noon, Kathleen R., Nichols, Joseph, Narasimhan, Diwahar, Woods, James H., Sunahara, Roger K.
Julkaistu 2011

Detection of G Protein-selective G Protein-coupled Receptor (GPCR) Conformations in Live Cells

Tekijä Malik, Rabia U., Ritt, Michael, DeVree, Brian T., Neubig, Richard R., Sunahara, Roger K., Sivaramakrishnan, Sivaraj
Julkaistu 2013

Rules of Engagement: GPCRs and G Proteins

Tekijä Glukhova, Alisa, Draper-Joyce, Christopher J., Sunahara, Roger K., Christopoulos, Arthur, Wootten, Denise, Sexton, Patrick M.
Julkaisussa ACS Pharmacol Transl Sci (2018)

Efficient Coupling of Transducin to Monomeric Rhodopsin in a Phospholipid Bilayer

Tekijä Whorton, Matthew R., Jastrzebska, Beata, Park, Paul S.-H., Fotiadis, Dimitrios, Engel, Andreas, Palczewski, Krzysztof, Sunahara, Roger K.
Julkaistu 2007

Effects of cocaine esterase following its repeated administration with cocaine in mice

Tekijä Ko, Mei-Chuan, Narasimhan, Diwahar, Berlin, Aaron A., Lukacs, Nicholas W., Sunahara, Roger K., Woods, James H.
Julkaistu 2009

Purification and Functional Reconstitution of Monomeric μ-Opioid Receptors: ALLOSTERIC MODULATION OF AGONIST BINDING BY G(i2)

Tekijä Kuszak, Adam J., Pitchiaya, Sethuramasundaram, Anand, Jessica P., Mosberg, Henry I., Walter, Nils G., Sunahara, Roger K.
Julkaistu 2009

A Bacterial Cocaine Esterase Protects Against Cocaine-Induced Epileptogenic Activity and Lethality

Tekijä Jutkiewicz, Emily M., Baladi, Michelle G., Cooper, Ziva D., Narasimhan, Diwahar, Sunahara, Roger K., Woods, James H.
Julkaistu 2008

The Ability of Bacterial Cocaine Esterase to Hydrolyze Cocaine Metabolites and Their Simultaneous Quantification Using High-Performance Liquid Chromatography-Tandem Mass Spectromet...

Tekijä Brim, Remy L., Noon, Kathleen R., Collins, Gregory T., Nichols, Joseph, Narasimhan, Diwahar, Sunahara, Roger K., Woods, James H.
Julkaistu 2011

Cell Permeable Cocaine Esterases Constructed by Chemical Conjugation and Genetic Recombination

Tekijä Lee, Tien-Yi, Park, Yoon Shin, Garcia, George A., Sunahara, Roger K., Woods, James H., Yang, Victor C.
Julkaistu 2012

Cocaine Esterase Prevents Cocaine-Induced Toxicity and the Ongoing Intravenous Self-Administration of Cocaine in Rats

Tekijä Collins, Gregory T., Brim, Remy L., Narasimhan, Diwahar, Ko, Mei-Chuan, Sunahara, Roger K., Zhan, Chang-Guo, Woods, James H.
Julkaistu 2009

Purification of family B G protein-coupled receptors using nanodiscs: Application to human glucagon-like peptide-1 receptor

Tekijä Cai, Yingying, Liu, Yuting, Culhane, Kelly J., DeVree, Brian T., Yang, Yang, Sunahara, Roger K., Yan, Elsa C. Y.
Julkaisussa PLoS One (2017)

A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein

Tekijä Whorton, Matthew R., Bokoch, Michael P., Rasmussen, Søren G. F., Huang, Bo, Zare, Richard N., Kobilka, Brian, Sunahara, Roger K.
Julkaistu 2007