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Detection of G Protein-selective G Protein-coupled Receptor (GPCR) Conformations in Live Cells

Although several recent studies have reported that GPCRs adopt multiple conformations, it remains unclear how subtle conformational changes are translated into divergent downstream responses. In this study, we report on a novel class of FRET-based sensors that can detect the ligand/mutagenic stabili...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Malik, Rabia U., Ritt, Michael, DeVree, Brian T., Neubig, Richard R., Sunahara, Roger K., Sivaramakrishnan, Sivaraj
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682522/
https://ncbi.nlm.nih.gov/pubmed/23629648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.464065
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