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Detection of G Protein-selective G Protein-coupled Receptor (GPCR) Conformations in Live Cells
Although several recent studies have reported that GPCRs adopt multiple conformations, it remains unclear how subtle conformational changes are translated into divergent downstream responses. In this study, we report on a novel class of FRET-based sensors that can detect the ligand/mutagenic stabili...
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| Main Authors: | , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Biochemistry and Molecular Biology
2013
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3682522/ https://ncbi.nlm.nih.gov/pubmed/23629648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.464065 |
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