Priming GPCR signaling through the synergistic effect of two G proteins

Although individual G-protein–coupled receptors (GPCRs) are known to activate one or more G proteins, the GPCR–G-protein interaction is viewed as a bimolecular event involving the formation of a ternary ligand–GPCR–G-protein complex. Here, we present evidence that individual GPCR–G-protein interacti...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Gupte, Tejas M., Malik, Rabia U., Sommese, Ruth F., Ritt, Michael, Sivaramakrishnan, Sivaraj
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2017
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389285/
https://ncbi.nlm.nih.gov/pubmed/28325873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617232114
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