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Structural Elements in the Gα(s) and Gα(q) C Termini That Mediate Selective G Protein-coupled Receptor (GPCR) Signaling
Although the importance of the C terminus of the α subunit of the heterotrimeric G protein in G protein-coupled receptor (GPCR)-G protein pairing is well established, the structural basis of selective interactions remains unknown. Here, we combine live cell FRET-based measurements and molecular dyna...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5016181/ https://ncbi.nlm.nih.gov/pubmed/27330078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.735720 |
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